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Large French Study Ties Higher Preservative Intake to Increased Type 2 Diabetes Risk

The Inserm-led analysis used brand-specific food diaries linked to additive databases to gauge long-term exposure.

Overview

  • Published in Nature Communications, the NutriNet-Santé cohort analysis of 108,723 adults recorded 1,131 new type 2 diabetes cases between 2009 and 2023.
  • Participants with the highest overall preservative intake had about a 47% higher incidence of type 2 diabetes compared with the lowest consumers.
  • Risk rose by 49% for non-antioxidant preservatives and by 40% for antioxidant additives when examined by category.
  • Twelve commonly consumed additives were individually linked to higher risk, including potassium sorbate (E202), sodium nitrite (E250), calcium propionate (E282), sodium ascorbate (E301), citric acid (E330) and phosphoric acid (E338).
  • Authors caution the findings are observational, urge replication and regulatory review, and advise favoring fresh, minimally processed foods.