Overview

• Over 2,000 genetic signals linked to blood pressure identified in a study involving more than one million participants.
• The study, led by Queen Mary University of London, enhances understanding of blood pressure regulation and offers new drug targets.
• Polygenic risk scores developed to predict individual blood pressure levels and hypertension risk, showing significant clinical potential.
• Findings highlight the need for more diverse genomic data to ensure the broad applicability of polygenic risk scores in routine healthcare.
• Research confirms polygenic risk scores are also relevant for individuals of African ancestry, addressing previous underrepresentation in genetic studies.