Overview
- The new analysis pooled 43 higher-quality studies, giving greatest weight to sibling-controlled designs to reduce confounding by genetics and family environment.
- Researchers found no significant increase in autism spectrum disorders, ADHD, or intellectual impairment linked to prenatal exposure when the medicine is used as directed.
- Study authors say earlier signals are better explained by maternal factors such as fever or underlying pain rather than a direct effect of the medication.
- Clinical experts and European regulators reiterate that this medicine remains the first-line option for treating pain or fever in pregnancy when indicated.
- The findings counter claims made in 2025 by President Donald Trump, as specialists warn that false alarms can deter needed treatment and that untreated fever in pregnancy carries documented risks.