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Lab Tests Show Wool-Derived Keratin Scaffolds Rebuild Tooth Enamel

Researchers demonstrate in-lab enamel-like mineralisation using wool-sourced proteins before moving to clinical development

Overview

  • King’s College London team extracted keratin from wool to form a crystal-like scaffold on tooth surfaces that attracts calcium and phosphate to rebuild enamel in laboratory tests.
  • The peer-reviewed study in Advanced Healthcare Materials confirms that keratin scaffolds halt early decay and seal nerve channels to relieve sensitivity.
  • Scientists envision both a daily toothpaste and a professional gel delivery, using abundant waste hair and wool as a sustainable, low-cost protein source.
  • Despite promising preclinical results, the approach requires manufacturing scale-up, allergenicity and safety assessments, and human trials before consumer use.
  • Authors estimate that with industry partnerships and completed clinical studies, keratin-based dental products could reach the market in two to three years pending regulatory approval.