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Kyoto Study Links Androgen Receptor Gene Variants to Cat Purring, Meowing and Aggression

Published in PLOS One, the research ties receptor polymorphisms to feline vocalization alongside aggression, highlighting plans to extend genetic analysis to wild cat relatives.

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Overview

  • Researchers at Kyoto University assessed genetic and behavioral data from 280 neutered mixed-breed cats through DNA analysis and owner surveys.
  • Cats carrying the short-type androgen receptor allele demonstrated higher purring scores and increased vocalization in males.
  • Female cats with the short-type variant showed elevated levels of stranger-directed aggression, revealing sex-specific genetic effects.
  • Comparisons with 11 wild Felidae species found domestic cats harbor longer receptor gene variants absent in their wild relatives, implicating domestication and selective breeding.
  • The team intends to broaden their study to other cat species and foresees that genotype-based care strategies could improve feline welfare outcomes.