Overview
- Purdy returns from shoulder and turf-toe setbacks after a limited practice Wednesday and a full session Thursday, ending a six-game absence.
- Mac Jones’ run as starter concludes at 5-3, with Shanahan saying choosing a healthy Purdy was not a hard decision.
- Wide receiver Ricky Pearsall is set to rejoin the lineup in Week 11 after missing time with a hamstring injury.
- Season-ending injuries to Nick Bosa and Fred Warner have thinned the defense, a factor cited in recent national power-ranking drops.
- Arizona will be without Marvin Harrison Jr. following appendicitis surgery, as San Francisco tries to gain ground on the Seahawks and Rams in the NFC West.