Keto Diet Shows Potential in Treating Autoimmune Disorders
Research from UC San Francisco reveals that the ketogenic diet may alleviate symptoms of multiple sclerosis in mice by altering gut microbiota.
- The study found that the ketogenic diet prompts the production of β-hydroxybutyrate (βHB), a ketone body that reduces inflammation in mice with multiple sclerosis.
- βHB influences the gut bacterium Lactobacillus murinus to produce indole lactic acid (ILA), which blocks activation of T helper 17 cells involved in autoimmune diseases.
- Mice unable to produce βHB experienced more severe symptoms, but supplementation with βHB improved their condition.
- Research suggests that diet-based supplements might offer a more tolerable treatment option for autoimmune disorders compared to strict dietary restrictions.
- Further testing in humans is needed to determine if these findings can be translated into effective treatments for autoimmune diseases.