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Ketamine Shows Promise for Treatment-Resistant Depression in Clinical Trials

New studies suggest ketamine may be more effective than traditional therapies, but results are mixed and further research is needed.

  • A mid-stage trial found slow-release ketamine pills safe but only effective at the highest dose.
  • Nearly 60% of participants in the ketamine trial dropped out due to lack of efficacy.
  • Ketamine may be more beneficial for outpatients and those with moderate symptoms compared to electroconvulsive therapy (ECT).
  • Patients with higher BMI showed better responses to ketamine treatment.
  • Further studies are required to validate these findings and guide personalized treatment plans.
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