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Katie Couric Parodies Sydney Sweeney Jeans Ad in PSA Urging Colon Cancer Screening at 45

Backed by the Colorectal Cancer Alliance with Ryan Reynolds' Maximum Effort, the Lead From Behind spot taps a viral moment to boost screening awareness.

Overview

  • Couric premiered the PSA on Sept. 25 during an appearance on NBC's Today, using the rollout to encourage viewers to book screenings.
  • The video mimics the American Eagle campaign’s look and voiceover, culminating with the on-screen line, “Katie Couric gets regular screenings.”
  • Couric’s script stresses that most colorectal cancers are not inherited and that everyone 45 and older should get checked.
  • The effort builds on her long advocacy following husband Jay Monahan’s 1998 death and her 2000 on-air colonoscopy credited with raising screening rates.
  • Health authorities cited in coverage say colorectal cancer often begins as removable polyps, remains a top cause of cancer deaths, and fewer than 60% of eligible Americans are up to date on screening.