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John Mellencamp Says Daughter Teddi Is 'Really Sick' With Cancer in Her Brain

The update follows her October report of no detectable disease after immunotherapy, with remission still undetermined.

Overview

  • Mellencamp shared the news on the Joe Rogan Experience, saying his daughter is suffering and has cancer in her brain.
  • His comments constitute the latest public update on her stage 4 condition.
  • Her illness began as stage 2 melanoma in 2022 and advanced to stage 4 after spreading to her brain and lungs in April 2025.
  • She has received immunotherapy, radiation, and approximately 17 surgeries as part of ongoing treatment.
  • In October 2025 she said scans showed no detectable cancer and that she would continue immunotherapy, noting she was not in remission and had previously been told her survival odds were about 50/50.