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John Mellencamp Says Daughter Teddi Is ‘Really Sick’ in New Brain Cancer Update

The remark contrasts with her October report of no detectable cancer during continued immunotherapy.

Overview

  • On Jan. 14, the musician told The Joe Rogan Experience that Teddi “has cancer in the brain” and is “suffering.”
  • The 44-year-old former Real Housewives star was diagnosed with melanoma in 2022 and by April 2025 reported metastases to her brain and lungs.
  • In October 2025, she said scans showed no detectable cancer, clarified she was not in remission, and planned to remain on immunotherapy for another year.
  • Her treatments have included brain surgery, radiation, and immunotherapy, with reports noting at least 17 melanoma removals and four brain tumors excised.
  • She has shared frequent updates via her podcast and social media, and has credited her father with daily support and help coordinating care.