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John Mellencamp Says Daughter Teddi Is 'Really Sick' as He Presses for Move Home During Cancer Treatment

The stark update follows her October scans showing no detectable cancer, with ongoing immunotherapy and brain lesions driving severe post‑treatment crashes.

Overview

  • On a Jan. 14 episode of The Joe Rogan Experience, John Mellencamp said Teddi has cancer in the brain and is "suffering right now."
  • Speaking on TODAY on Jan. 16, he urged her to move back to Indiana and described cycles where immunotherapy leaves her feeling "like hell" for about four days.
  • Teddi’s melanoma, first disclosed in 2022, progressed to Stage 4 in 2025 after spreading to her lungs and brain, leading to brain surgery, radiation and immunotherapy.
  • In October 2025, she reported scans showing no detectable cancer but emphasized she was not in remission and would stay on immunotherapy for at least a year.
  • She has previously said doctors gave her a roughly 50/50 prognosis when the disease metastasized, underscoring the long and uncertain path to remission.