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James Harrison, Whose Rare Blood Saved 2.4 Million Babies, Dies at 88

The Australian donor's unique antibodies were key to developing a life-saving treatment for Rhesus disease, transforming neonatal care worldwide.

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11 May 2018, Australia, Sydney: James Harrison lies on a stretcher during his last blood donation. He is surrounded by mothers and their children. 63 years after his first blood donation, Harris gave his last donation. 1173 is the total number of donations of blood plasma the 81-year-old has made. According to calculations of the Red Cross, Harris has helped more than two million mothers in Australia deliver their babies safely. Photo: Subel Bhandari/dpa (Photo by Subel Bhandari/picture alliance via Getty Images)

Overview

  • James Harrison, known as the 'Man with the Golden Arm,' donated blood plasma over 1,100 times between 1954 and 2018, saving an estimated 2.4 million babies.
  • His blood contained a rare anti-D antibody, which was used to create a treatment preventing Rhesus disease, a condition where a mother's immune system attacks her fetus's red blood cells.
  • Harrison began donating blood at 18 after receiving life-saving transfusions during lung surgery at the age of 14, inspiring his lifelong commitment to helping others.
  • The anti-D treatment, developed in the 1960s using Harrison's plasma, has protected countless mothers and babies from severe complications, miscarriages, and stillbirths.
  • Harrison passed away peacefully in his sleep on February 17, 2025, leaving behind a legacy of unparalleled generosity and a challenge to find new donors with similarly rare antibodies.