Overview
- Researchers analyzed outcomes from nearly 20,000 SARS-CoV-2–affected pregnancies between April 2021 and December 2022 across eight provinces and one territory.
- Vaccinated pregnant people were about 60% less likely to be hospitalized and 90% less likely to require intensive care than those unvaccinated at infection.
- Preterm birth risk dropped by roughly 20% during the Delta period and 36% during Omicron for those vaccinated.
- Vaccination administered during pregnancy was associated with even lower rates of preterm birth and stillbirth than vaccination only before pregnancy.
- The authors say the findings support vaccination in pregnancy as some U.S. guidance has removed routine recommendations for healthy pregnant women and is facing legal challenges.