Particle.news
Download on the App Store

JAMA Oncology Study Links High Ultra‑Processed Food Intake to Precancerous Colon Polyps in Younger Women

A 24‑year Nurses’ Health Study II analysis found a 45% higher risk of conventional adenomas at the highest intakes, though the observational, mostly white cohort calls for replication.

Overview

  • Researchers reviewed 29,105 participants who completed food questionnaires every four years and underwent at least two lower endoscopies before age 50.
  • Women consuming about 10 daily servings of ultra‑processed foods had a 45% higher risk of conventional adenomas than those averaging about three servings.
  • On average, participants reported 5.7 servings of ultra‑processed foods per day, estimated to be roughly 35% of total daily calories.
  • The association persisted after accounting for body mass index, type 2 diabetes and fiber intake, and no link was found with serrated lesions.
  • Authors advise cutting back on ultra‑processed foods as a pragmatic step while investigating other drivers of early‑onset colorectal cancer and refining how these products are classified.