Overview

• Kickoff is Sunday, Oct. 12 at 1:00 PM ET at EverBank Stadium, airing on FOX with Chris Myers and Kristina Pink on the call as a third crew member remains to be determined.
• Jacksonville enters 4-1 on a three-game win streak after a comeback over the Chiefs, while Seattle is 3-2 following a last-second loss to the Buccaneers.
• USA TODAY’s picks largely lean Jaguars by a small spread, with multiple panelists listing Jacksonville at -1.5, signaling expectations for a close game.
• Analysts spotlight the Jaguars’ defense, reported at an NFL-best 14 takeaways, as a key factor against a Seahawks offense that must limit mistakes.
• Quarterback form is central to the matchup, with Trevor Lawrence coming off a multi-score rally and Sam Darnold posting 341 yards and four TDs before a late interception in Week 5.