Overview

• An unusual antibody surfaced in the patient’s pre-surgery tests in 2011 but lacked resources for further study until 2019.
• Researchers used high-throughput DNA sequencing to pinpoint a novel genetic mutation defining the new antigen.
• The woman inherited Gwada negative from both parents, each carrying the same mutated gene.
• Official ratification by the International Society of Blood Transfusion in early June makes it the world’s 48th recognized blood group system.
• Scientists are now seeking additional carriers to improve matching and care for patients with rare blood types.