Overview
- IOF estimates equate to about 37 million osteoporotic fractures each year and roughly 500 million people affected worldwide, many without a diagnosis.
- In Mexico, about one in three women and one in five men over 50 live with the disease, with demographic aging expected to raise future risk.
- Post‑menopausal estrogen decline accelerates bone loss, and some women can lose up to 25% of bone mass within a decade after menopause, according to NIH and IMSS.
- Experts highlight major care gaps: four in five patients do not link fractures to osteoporosis, more than 57% of those at risk go untreated, and DEXA is the gold‑standard test.
- Prevention focuses on adequate calcium and vitamin D, moderate sun exposure, and weight‑bearing exercise, while RANK‑L–targeting monoclonal antibodies have shown fracture reductions up to 68%; clinicians also warn of underdiagnosis in men with about 20% dying in the first year after a hip fracture.