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Investigators Send Evidence to Four Specialized Labs as Nancy Guthrie Remains Missing

Niche DNA work on rootless hair and complex mixtures aims to produce leads through genetic genealogy.

Overview

  • Nancy Guthrie, 84, was last seen on the evening of January 31 and her family reported her missing on February 1, and she remains unlocated nearly nine months later.
  • Authorities have released doorbell images of a masked person on Guthrie’s porch and published alleged ransom notes, but no suspect has been publicly identified or arrested.
  • Pima County Sheriff Chris Nanos confirmed evidence has been sent to four specialized laboratories, including a private Deerfield Beach Florida lab and facilities in Kansas and San Francisco.
  • Detectives traveled to the Florida lab to pursue low-copy-number and rootless-hair DNA testing, while retired investigators say one lab is examining a DNA mixture of up to four people and are surprised there is no genetic-genealogy hit so far.
  • Specialized labs use niche extraction and mixture-analysis techniques that can take weeks or months and may or may not yield profiles usable for genetic genealogy, a reality that shapes investigators’ timelines and the family’s ongoing $1 million reward appeal.