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Intermittent Fasting Found to Boost Libido in Male Mice, Study Suggests Human Potential

Research links long-term fasting to reduced serotonin levels and increased sexual activity in male mice, paving the way for potential treatments for low libido in humans.

Empty plate with alarm clock on green background, intermittent fasting concept.
Medical Research Scientists Examines Laboratory Mice kept in a Glass Cage. She Works in a Light Laboratory.

Overview

  • A study published in Cell Metabolism shows that male mice on a 24-hour intermittent fasting cycle exhibit significantly increased sexual activity after six months.
  • The effect is attributed to reduced serotonin levels caused by fasting, which lowers dietary tryptophan intake and diminishes inhibitory effects on sexual behavior.
  • Researchers confirmed the increased libido is driven by behavioral changes rather than improvements in sperm quality or hormone levels.
  • The findings suggest potential human applications, including treatments for hypoactive sexual desire disorder (HSDD), though human trials are needed for validation.
  • The international study was conducted by researchers from DZNE, Qingdao University, and the University of Health and Rehabilitation Sciences.