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Innovative Weight-Loss Drug Targets Brain's Plasticity for Enhanced Effectiveness

Researchers develop a new treatment combining GLP-1 and NMDA receptor blockers, showing promising results in preclinical trials.

  • The drug employs a 'Trojan Horse' method to deliver molecules directly to the brain's appetite control center.
  • Mice treated with the new drug lost twice as much weight as those on existing GLP-1 therapies.
  • Potential for lower dosages and reduced side effects compared to current treatments.
  • The approach could pave the way for new treatments for neurodegenerative and psychiatric disorders.
  • Human clinical trials are expected to start soon, with market availability projected in eight years.
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