Innovative Weight-Loss Drug Targets Brain's Plasticity for Enhanced Effectiveness
Researchers develop a new treatment combining GLP-1 and NMDA receptor blockers, showing promising results in preclinical trials.
- The drug employs a 'Trojan Horse' method to deliver molecules directly to the brain's appetite control center.
- Mice treated with the new drug lost twice as much weight as those on existing GLP-1 therapies.
- Potential for lower dosages and reduced side effects compared to current treatments.
- The approach could pave the way for new treatments for neurodegenerative and psychiatric disorders.
- Human clinical trials are expected to start soon, with market availability projected in eight years.