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8mo ago

Innovative Implant Detects and Reverses Opioid Overdoses

Researchers unveil a subcutaneous device that monitors vital signs and administers naloxone automatically to prevent fatalities.

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The device, which is about the size of a stick of gum, can be implanted under the skin, where it monitors heart rate, breathing rate, and other vital signs. When it determines that an overdose has occurred, it rapidly pumps out a dose of naloxone.
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Overview

  • The iSOS device uses multiple sensors to detect signs of opioid overdose and delivers naloxone within 10 seconds.
  • Developed by Brigham and Women's Hospital and MIT, the device aims to reduce the need for bystander intervention.
  • Initial tests showed a 96% success rate in reversing overdoses in animal models.
  • The device's algorithms can differentiate between opioid overdose and other conditions like sleep apnea.
  • Future developments may include features like automated emergency calls and multiple naloxone doses.