Overview
- San Francisco (5-3) plays New York (2-6) at MetLife Stadium on Sunday at 1 p.m. ET, with BetMGM listing the 49ers as 2.5-point favorites.
- QB Brock Purdy remains limited with a toe injury and is officially questionable, while Mac Jones has started in his place as the staff weighs this week’s call.
- The 49ers continue without defensive cornerstones Fred Warner and Nick Bosa as the pass rush lags, but they added Keion White for depth and saw Yetur Gross-Matos and others return to practice in limited work; Bryce Huff is not expected to play.
- The Giants’ offense is thin with rookie Cam Skattebo out for the season, but rookie starter Jaxson Dart has eight TDs in five starts and CB Cor'Dale Flott is in concussion protocol.
- Coaches and oddsmakers point to New York’s disruptive front—anchored by Dexter Lawrence with edge help from Brian Burns and Kayvon Thibodeaux—as a central test for a 49ers team leaning more on Christian McCaffrey, with the result likely to shape trade-deadline thinking.
 
 