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India Rules Out Toxic Glycols in Cough Syrups Linked to Child Deaths as DGHS Tightens Pediatric Guidance

Investigators are expanding clinical and environmental testing after initial central lab results found no DEG or EG in syrups collected from affected districts.

Overview

  • Union Health Ministry said joint testing by national agencies and the MP drug regulator found no diethylene glycol or ethylene glycol in cough syrup samples from Madhya Pradesh and Rajasthan.
  • DGHS advised against prescribing or dispensing cough and cold medicines to children under two years and urged cautious, short-duration use only after clinical evaluation in older children.
  • One patient sample tested positive for leptospirosis, and teams are analyzing water, vectors, and respiratory specimens as part of a multi-agency probe into alternative causes.
  • Rajasthan’s health department said two reported child deaths were not tied to state-supplied medicines, noting the syrup was given at home without a doctor’s prescription and that the formulation involved dextromethorphan, which is not recommended for children.
  • Tamil Nadu’s Drugs Control Department reported diethylene glycol adulteration in one Coldrif batch (SR-13) and ordered stop-production with a show-cause notice, creating a discrepancy with central findings that is driving further regulatory review.