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Imperial Model Warns of 480 Measles Deaths if England’s MMR Uptake Stalls

UKHSA is pushing pre‑term vaccination because two‑dose coverage lags the 95% threshold.

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Overview

  • Imperial College modelling projects a worst‑case toll of about 480 avoidable deaths and 390,000 additional cases over 20 years if uptake does not improve and no outbreak response occurs.
  • England’s two‑dose MMR coverage is about 85% with some London areas near 70%, below the World Health Organization’s 95% level needed to prevent sustained transmission.
  • This summer’s rise includes 674 confirmed cases in England so far this year, with 111 in the North West, and a child’s death and other severe illnesses reported at Alder Hey in Liverpool.
  • NHS England’s 2023–24 catch‑up campaign delivered roughly 180,000 extra MMR vaccinations, and UKHSA has moved the first dose to 18 months to boost protection earlier.
  • Experts cite access barriers and misinformation for low uptake, recommend targeted outreach and easier appointments, note a potential £290 million economic cost, and some call for debate on mandates or financial penalties.