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iCares Smart Bandage Demonstrates Real-Time Chronic Wound Monitoring in Human Trials

Caltech and USC researchers unveil a wearable device that detects infection biomarkers early, predicts healing trajectories, and manages wound fluid with advanced microfluidics and AI.

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Overview

  • The iCares smart bandage successfully completed human feasibility trials on 20 chronic wound patients, providing continuous wound fluid analysis.
  • Using microfluidics, the bandage removes excess moisture and ensures only fresh wound fluid is analyzed for accurate biomarker detection.
  • The device identifies inflammation and infection markers, such as nitric oxide and hydrogen peroxide, one to three days before symptoms appear.
  • A machine-learning algorithm integrated into the bandage predicts wound healing timelines with accuracy comparable to expert clinicians.
  • Constructed from low-cost, 3D-printed biocompatible materials, the bandage combines disposable sensor arrays and reusable wireless electronics for real-time data transmission.