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Ibogaine Shows Promise in Treating PTSD, Depression, and Anxiety in Veterans

Stanford researchers find significant improvements in neuropsychiatric symptoms and functioning among veterans with traumatic brain injuries after treatment with ibogaine.

  • Stanford researchers have discovered that ibogaine, a plant-based psychoactive compound, combined with magnesium, effectively reduces PTSD, anxiety, and depression in veterans with traumatic brain injuries (TBIs).
  • The study involved 30 U.S. special forces veterans and showed dramatic improvements in neuropsychiatric symptoms and functioning, with no serious side effects.
  • Ibogaine is a naturally occurring compound found in the roots of the African shrub iboga, and it has been used for centuries in spiritual and healing ceremonies.
  • Before treatment, the veterans had an average disability rating of 30.2 on the disability assessment scale, equivalent to mild to moderate disability. One month after treatment, that rating improved to 5.1, indicating no disability.
  • Participants experienced average reductions of 88% in PTSD symptoms, 87% in depression symptoms and 81% in anxiety symptoms relative to how they were before ibogaine treatment.
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