Overview

• Researchers reported that high blood pressure, pre-diabetes or type 2 diabetes, and low HDL cholesterol were linked to roughly 40%, 25%, and 15% higher all-cause mortality, respectively, in adults with the liver condition.
• Each additional cardiometabolic risk factor present raised the likelihood of death by about 15%, indicating a clear cumulative burden.
• Obesity showed a BMI-dependent gradient, with higher body mass index associated with greater mortality risk.
• The associations held regardless of sex, race or ethnicity and were independent of how many or which combinations of risk factors were present.
• The team analyzed NHANES data from 1988–2018, identifying about 21,000 affected adults among 134,515 participants, and they plan follow-up studies on genetic, dietary and alcohol influences.