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HPV Study Finds Community Protection as Pakistan Extends Vaccination Drive After Mass Refusals

High, gender-neutral uptake appears to drive indirect protection for those who are unvaccinated.

Overview

  • The JAMA Pediatrics study tracked 2,335 adolescents and young women in Cincinnati from 2006 to 2023, as vaccination coverage rose to about 82%.
  • HPV infections fell by roughly 76%–98% in vaccinated women depending on vaccine type, while unvaccinated women saw 72%–76% declines for vaccine‑covered strains.
  • Researchers attribute the community protection to high coverage that includes boys, cautioning that herd effects are dynamic and could wane if uptake drops, with limited evidence to date for the 9‑valent vaccine’s indirect impact.
  • Pakistan’s national campaign, launched on Sept. 15 to reach about 11.7 million girls ages 9–14, has recorded more than 3.6 million parental refusals, with officials reporting over 7.7 million vaccinations so far.
  • The government has extended the campaign by two years and plans to move the shot into the Expanded Program on Immunisation after December, as officials intensify outreach to counter misinformation such as false infertility claims.