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HIV Drugs Linked to Lower Alzheimer's Disease Risk, Study Finds

A new study reveals that reverse transcriptase inhibitors, commonly used in HIV treatment, may significantly reduce the incidence of Alzheimer's disease.

  • Research led by Sanford Burnham Prebys indicates that HIV medications may lower Alzheimer's disease occurrence in older HIV-positive patients.
  • The study analyzed over 225,000 medical records, finding a lower rate of Alzheimer's among those using reverse transcriptase inhibitors.
  • This discovery builds on previous research showing similar enzyme activity in Alzheimer's and HIV, suggesting a potential therapeutic overlap.
  • While preliminary, these findings could lead to repurposing HIV drugs for Alzheimer's, highlighting the need for further clinical trials.
  • The research was supported by the National Institute on Aging and other foundations, emphasizing its significance and potential impact.
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