Overview

• Research led by Sanford Burnham Prebys indicates that HIV medications may lower Alzheimer's disease occurrence in older HIV-positive patients.
• The study analyzed over 225,000 medical records, finding a lower rate of Alzheimer's among those using reverse transcriptase inhibitors.
• This discovery builds on previous research showing similar enzyme activity in Alzheimer's and HIV, suggesting a potential therapeutic overlap.
• While preliminary, these findings could lead to repurposing HIV drugs for Alzheimer's, highlighting the need for further clinical trials.
• The research was supported by the National Institute on Aging and other foundations, emphasizing its significance and potential impact.