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Higher Late-Pregnancy Cortisol Tied to Earlier Baby Teeth, Study Finds

Researchers say the link is observational, with larger studies needed to test mechanisms, causality, generalizability.

Overview

  • The peer-reviewed analysis, published November 18 in Frontiers in Oral Health, followed 142 socioeconomically disadvantaged mother–infant pairs in the U.S.
  • Infants of mothers with the highest measured cortisol in late pregnancy had about four more erupted teeth at six months than those of mothers with the lowest levels.
  • Dentists counted erupted primary teeth at 1, 2, 4, 6, 12, 18, and 24 months, documenting wide variation in teething timelines across the cohort.
  • Maternal diagnoses of depression or anxiety showed no association with measured hormone concentrations or the number of erupted teeth at any age.
  • Weaker associations appeared for estradiol, progesterone, testosterone, and triiodothyronine at specific ages, with authors hypothesizing roles for mineral metabolism and bone-cell activity while urging confirmatory, broader studies.