High-Potency Cannabis Use Linked to Unique DNA Changes and Psychosis Risk

Research reveals that frequent use of cannabis with high THC levels can alter DNA, potentially identifying users at increased risk for psychosis.

A study by King's College London and the University of Exeter found that high-potency cannabis use leaves distinct molecular marks on DNA.
The research highlights changes in genes related to the immune system and energy production, particularly affecting the CAVIN1 gene.
DNA methylation, an epigenetic modification, was observed to differ between cannabis users with and without psychosis experiences.
The findings suggest the potential for developing DNA blood tests to identify cannabis users at higher risk of psychosis.
The study underscores the need to understand cannabis's biological impact, especially as high-potency strains become more prevalent.