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High-Fat Cheese and Cream Linked to Lower Dementia Risk in 25-Year Swedish Study

Experts caution that the results show association rather than cause, urging replication before altering diets.

Overview

  • An analysis in Neurology of 27,670 adults followed for about 25 years found a 13% lower all-cause dementia risk with at least 50 g/day of high-fat cheese and a 16% lower risk with at least 20 g/day of high-fat cream.
  • The strongest signal was for vascular dementia, where higher high-fat cheese intake was associated with a 29% lower risk after adjustments.
  • A lower Alzheimer’s risk was observed only among participants without the APOE e4 gene variant, a known genetic risk factor.
  • No association was found for low-fat dairy, milk, butter, or fermented milk products including yogurt, kefir, and buttermilk.
  • Researchers and independent experts highlighted limitations such as baseline self-reported diet, healthier cardiometabolic profiles among higher cheese consumers, and Swedish eating habits that may limit generalizability.