High Doses of ADHD Medications Linked to Increased Risk of Psychosis and Mania

New study reveals a five-fold increase in psychosis risk for adults taking high doses of amphetamine-based ADHD medications.

Adults taking 30 mg or more of dextroamphetamine face a five-fold increased risk of developing psychosis or mania.
81% of psychosis or mania cases could potentially be avoided by lowering the dose of amphetamine-based medications.
The study found no significant risk increase for psychosis or mania with the use of methylphenidate (Ritalin).
The research analyzed electronic health records from Mass General Brigham hospitals, focusing on patients aged 16 to 35.
Doctors are advised to monitor patients closely and consider lower doses, especially for those at higher risk for mental health issues.