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4d ago

High-Dose Turmeric Pills Trigger Severe Liver Injury and Prompt FDA Review

Physicians warn piperine-enhanced curcumin products amplify toxicity in the absence of FDA premarket review

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Overview

  • Katie Mohan, 57, was hospitalized after daily high-dose turmeric pills containing black pepper led to acute hepatitis and potential transplant evaluation at NYU Langone.
  • She has been discharged with falling liver enzyme levels and reported the product to the Food and Drug Administration for investigation.
  • Research in The American Journal of Medicine identified 10 US cases of turmeric-associated liver injury from 2004 to 2022, including one fatality.
  • Experts, including Dr. Jen Gunter, warn that piperine can boost curcumin absorption by up to 2,000 percent, heightening toxicity risks.
  • Physicians and health officials are calling for stricter regulation of high-dose turmeric formulations under current supplement oversight loopholes.