Overview
- HHS has canceled its $590 million BARDA award to Moderna after a rigorous review deemed the mRNA H5N1 program scientifically and ethically unjustifiable.
- Moderna reported that its Phase 1/2 trial in roughly 300 adults achieved a 98 percent immune response and demonstrated a favorable safety profile.
- The funding cut withdraws two Biden-era awards totaling $766 million—$176 million in July 2024 and $590 million in January 2025—for late-stage development and stockpiling readiness.
- Health Secretary Robert F. Kennedy Jr.’s deep skepticism of mRNA vaccine technology has prompted a broader Trump administration review of previous pandemic preparedness contracts.
- With at least 70 U.S. infections and one death, public health experts warn that scaling back mRNA efforts could slow response if H5N1 mutates for human transmission.