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HHS Launches 'OneHHS' AI Strategy to Centralize Adoption Across the Department

The plan prioritizes internal efficiency, signaling a sharp expansion of AI deployments in 2025.

U.S. Secretary of Health and Human Services Robert F. Kennedy Jr. speaks during the Western Governors' Association meeting Thursday, Nov. 20, 2025, in Scottsdale, Ariz. (AP Photo/Rebecca Noble)

Overview

  • HHS released the departmentwide “OneHHS” roadmap to coordinate AI across CDC, CMS, FDA, NIH and other divisions through a centralized infrastructure.
  • The plan, led by acting chief AI officer Clark Minor, rests on five pillars: governance and risk, infrastructure and platforms, workforce development, research reproducibility, and modernization of care and public health.
  • HHS will stand up a senior governance board, create a departmentwide AI tool inventory, and train staff under a try‑first culture that already includes employee access to ChatGPT.
  • The strategy fulfills Trump administration directives and OMB guidance, begins with internal efficiency goals, and sets the stage for private‑sector collaboration on priority health problems.
  • Lawmakers praised the move, while experts warned about protecting sensitive medical data and gaps in safeguards for aggregated information; HHS reports 271 AI projects in FY2024 and projects roughly 70% growth in 2025.