Overview

• Researchers restructured tumor categories in 80 registries across 31 countries to align data with modern diagnostics for more accurate survival comparisons.
• Analysis of records from over 30,000 children diagnosed between 1998 and 2013 shows overall survival for the four most common pediatric brain tumors has improved.
• Country-to-country differences in survival narrowed, indicating broadly similar access to pediatric oncology care across Europe.
• For the first time, population-based cure fractions were estimated for low-grade gliomas, medulloblastomas, ependymomas and high-grade gliomas, providing new benchmarks for treatment success.
• Despite overall progress, five-year survival for high-grade gliomas remains alarmingly low, underscoring the urgent need for novel therapies and enhanced registry practices.