Overview

• Protein TGM from Heligmosomoides polygyrus accelerates wound closure and promotes tissue regeneration.
• TGM-treated wounds in mice showed less scarring and regenerated hair follicles, indicating improved skin healing.
• The protein interacts with TGF-β receptors, reprogramming immune cells to favor regeneration over fibrosis.
• Study findings suggest potential for developing TGM as a therapeutic for human wound healing.
• Further research is needed to confirm safety and effectiveness of TGM in human patients.