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Gut Bacteria Sequester PFAS and Boost Excretion in Mice

The Nature Microbiology publication underpins Cambiotics’ plans for human trials leading to a 2026 probiotic offering

Illustration of potatoes underground surrounded by PFAS
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Overview

  • Certain human gut bacterial species can absorb per- and polyfluoroalkyl substances within their cells across a range of concentrations
  • In mice colonized with nine of these strains, the microbes captured 25 to 74 percent of ingested PFAS and eliminated them via fecal excretion
  • The study, published in July in Nature Microbiology, offers the first evidence of microbial PFAS bioaccumulation in a living host
  • Researchers including Kiran Patil and Anna Lindell have co-founded Cambiotics to translate these findings into targeted probiotic interventions
  • Cambiotics intends to begin human testing of these PFAS-sequestering microbes and launch its first probiotic product by 2026