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Gut Bacteria Capture PFAS in Mice, Prompting Probiotic Startup

Following a Nature Microbiology paper validating PFAS removal by gut microbes in mice, researchers formed Cambiotics to prepare for human trials

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Overview

  • Certain human gut bacterial species absorb PFAS into intracellular clumps, shielding the microbes from toxin exposure.
  • In mouse experiments, the introduced bacteria sequestered 25%–74% of ingested PFAS and expelled them in feces regardless of dose.
  • The findings, published July 1 in Nature Microbiology, mark the first demonstration of microbial PFAS bioaccumulation in a living mammalian model.
  • Lead authors Kiran Patil and Anna Lindell co-founded Cambiotics to develop probiotic formulations that boost PFAS-absorbing microbes in the gut.
  • Cambiotics plans to initiate human testing to verify PFAS removal and aims to bring its first probiotic supplement to market by 2026.