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Guidance Confirms Magnesium Supplements Safe Up to 250 mg Daily and Highlights Blood Pressure Benefits

Recent studies suggest supervised doses of 300–600 mg can lower diastolic pressure by about 10 mm Hg without significant toxicity in healthy adults.

Overview

  • Official bodies recommend daily magnesium intakes of 300 to 420 mg, with supplements up to 250 mg per day considered safe for individuals with normal kidney function.
  • The Bundesinstitut für Risikobewertung capped blind supplement doses at 250 mg per day to avoid diarrhea, which can occur at higher intakes.
  • Clinical trials using 360 mg per day magnesium achieved an average 10 mm Hg reduction in diastolic blood pressure in hypertensive patients.
  • Toxic hypermagnesemia is rare and generally arises only from severe renal impairment or extreme intakes above 2,500 mg per day.
  • Variables such as stress, sweat loss, gastrointestinal health, medication interactions and supplement form influence absorption and tolerance.