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GSK Taps Luke Miels as Next CEO Starting Jan. 1, 2026

Shares rose about 3% after the announcement, signaling support for GSK’s pharma-first strategy.

Overview

  • Emma Walmsley will leave the board on Dec. 31, 2025 and remain with GSK through Sept. 30, 2026 to support the transition.
  • Chief commercial officer since 2017, Luke Miels has been tasked with delivering annual sales of more than £40 billion by 2031.
  • The succession crowns a strategic overhaul under Walmsley that included the 2022 Haleon spin-off and increased R&D to rebuild a late-stage pipeline.
  • GSK’s handover unfolds as the company addresses U.S. policy risk, including threatened 100% tariffs on branded drugs and a pledged $30 billion U.S. investment over five years.
  • Analysts note progress in specialty medicines alongside challenges such as a 2028 U.S. exclusivity loss for HIV drug dolutegravir and prior Zantac settlements totaling about $2.3 billion.