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Groundbreaking 'Third Nostril' Surgery Achieves One-Year Tumor-Free Milestone

University of Maryland surgeons successfully removed a spinal chordoma through a patient’s eye socket, with no recurrence nearly a year later and potential applications for other complex tumors.

Close-up of human eye (Stock image).
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Overview

  • The innovative 'third nostril' technique involved accessing a spinal chordoma via the eye socket, avoiding traditional high-risk approaches.
  • The 19-hour surgery required millimeter-scale precision to shift the eyeball safely and remove the tumor near critical neurovascular structures.
  • Extensive preoperative rehearsals on cadaver heads ensured the procedure's safety and feasibility, minimizing risks of paralysis or brainstem stroke.
  • Post-surgery reconstruction used bone grafts, titanium hardware, and mesh, followed by proton therapy to target any remaining tumor cells.
  • One year after the procedure, patient Karla Flores remains tumor-free, as surgeons explore broader applications of this minimally invasive approach.