Groundbreaking Lupus Treatment Trial Offers Hope for Drug-Free Remission

The NHS is testing CAR T-cell therapy, a treatment previously used for cancer, to potentially eliminate lifelong medication for lupus patients.

• The trial, led by London Hospitals, involves genetically modifying immune cells to target and destroy lupus-causing cells.
• Three patients in the UK, including 50-year-old Katie Tinkler, have received the treatment, with hopes of achieving remission from systemic lupus erythematosus (SLE).
• CAR T-cell therapy has shown promise in Germany, where patients have entered remission and no longer require lupus medications.
• Lupus, an autoimmune disease, can cause severe damage to organs such as the heart, lungs, brain, and kidneys, requiring lifelong medication.
• The trial aims to revolutionize lupus treatment, offering a potential cure and newfound hope for the 70,000 lupus patients in the UK.

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