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Grey's Anatomy Season 22 Premieres Oct. 9 on ABC as Series Returns to Explosion Aftermath

Showrunner Meg Marinis frames the new season as a long road to recovery focused on hope.

Overview

  • The season debuts in the U.S. on Oct. 9 on ABC, streams next day on Hulu, and reaches Disney+ internationally starting Oct. 10.
  • Ellen Pompeo returns as Meredith Grey alongside the main ensemble, maintaining cast continuity into the new chapter.
  • An 18-episode run will roll out weekly, continuing the show’s standard release cadence.
  • ABC’s trailer spotlights the harrowing fallout at Grey Sloan, raising unresolved questions about who survived.
  • Reporting names six characters still in danger—Link, Webber, Beltran, Millin, Lucas and Bailey—while actor Jason George has teased a “deadly” premiere and suggested not everyone makes it.