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Grey’s Anatomy Season 22 Premieres Oct. 9 as Explosion Fallout Puts Key Doctors at Risk

The new run centers on Grey Sloan’s recovery after last season’s blast, with showrunner Meg Marinis signaling a tone of resilience.

Overview

  • Premiere is Thursday, Oct. 9 at 10 p.m. ET on ABC in the U.S., with next‑day streaming on Hulu and international rollout from Oct. 10 on Disney+; CTV streams episodes free in Canada the day after airing.
  • ABC’s official trailer depicts the aftermath inside Grey Sloan and raises questions over injuries and potential fatalities without confirming outcomes.
  • TV Insider reporting says six doctors remain in danger in promotional materials: Atticus “Link” Lincoln, Richard Webber, Monica Beltran, Jules Millin, Lucas Adams and Miranda Bailey.
  • Jason George, who plays Ben Warren, told Soaps.com that “not everybody makes it out,” teasing a deadly premiere without naming who is affected.
  • The season spans 18 episodes under Meg Marinis, who says the story will follow a long road to recovery and hope, with Ellen Pompeo and the core ensemble returning.