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4h ago

Grey’s Anatomy Season 22 Premiere Resolves Cliffhanger, Launches 18-Episode Run

The premiere closes the cliffhanger to launch an 18-episode season that reaches its 450th episode next week.

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Natalie Morales as Monica Beltran on ABC's "Grey's Anatomy."
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Overview

  • Season 22 premiered Oct. 9 at 10 p.m. ET on ABC, with new episodes airing Thursdays and streaming on Hulu the following day.
  • ABC confirms an 18-episode season, with Episode 2 on Oct. 16 marking the series’ 450th installment, titled “We Built This City.”
  • The opener picks up seconds after last season’s hospital blast, centering on emergency response and long-term recovery arcs without resolving every loss.
  • Showrunner Meg Marinis says the writers wrestled with the fallout and ultimately concluded they could not save everyone.
  • Ellen Pompeo’s Meredith Grey has a prominent presence, and the post-episode teaser signals Kelly McCreary’s Maggie Pierce is set to appear next week.