Overview

• ABC has officially renewed Grey’s Anatomy for its 22nd season, expected to premiere in fall 2025, though no exact date has been confirmed.
• The Season 21 finale featured a high-stakes hostage situation and a hospital explosion, leaving the survival of several key characters uncertain.
• Ellen Pompeo will reprise her role as Meredith Grey in a reduced capacity, appearing in seven episodes while continuing as a narrator and executive producer.
• Showrunner Meg Marinis has teased significant consequences from the finale’s events, with the explosion set to shape the narrative of Season 22.
• The upcoming season will explore the fallout from the finale while introducing new character dynamics as Grey Sloan Memorial Hospital rebuilds.