Grey’s Anatomy Returns with High-Stakes Midseason Premiere

The medical drama resumes after a tense cliffhanger involving Jo Wilson's pregnancy and a dangerous hostage situation.

The Season 21 midseason premiere of Grey’s Anatomy airs Thursday, March 6, 2025, at 10 p.m. ET on ABC.
Jo Wilson, pregnant with twins, faces complications following a violent hostage situation in the fall finale.
A tense hospital scene reveals Jo's pregnancy may be at risk, with Miranda Bailey stepping in to provide care.
The episode will explore the aftermath of the robbery, including its impact on Jo’s relationship with Atticus Lincoln.
Season 21 will feature 18 episodes, with Meredith Grey appearing in at least seven, continuing her limited role.